of a research group with the goal to determine how we could mini-
mize foreign body response while maintaining structural integrity. In
short, what would the perfect mesh look like? What would it be made
of? How would it be structured?
It was a great goal, but the answer turned out to be elusive for one
very good reason. There is no ideal hernia mesh. Case in point. At the
time there were a bunch of newer lightweight, wider pore-size meshes
on the market. For some people, they worked great. But in other peo-
ple, the mesh simply wasn't strong enough to hold up. Their bodies
reacted in ways that led to holes and mechanical failures.
No size fits all
What we now know is that mesh can have very different levels of
interaction in differ-
ent patients. The only
general statement
you can make about
mesh is that the same
mesh and the same
technique can pro-
duce dramatically dif-
ferent outcomes in
different patients.
Unfortunately, in
some patients, mesh
and other factors can
contribute to devas-
tating outcomes, the
worst of which is
severe and disabling
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