Manufacturer
Dantrolene dose per vial
Number of vials for initial dose*
Water to reconstitute 1 vial
Vials required to stock
Price
Shelf life
US WorldMeds Par Pharmaceutical Eagle Pharmaceuticals
20 mg 20 mg 250 mg
8 vials (480 mL) 8 vials (480 mL) 1 vial (5 mL)
60 mL 60 mL 5 mL
36 36 3
$3,000 $3,000 $6,900
3 years 3 years 2 years
Your Guide to MH Antidotes
Ryanodex is the first new drug in more than 7 years for MH, a life-
threatening complica-
tion of anesthesia.
Here's how Ryanodex
compares to long-
standing dantrolene
formulations Revonto
and Dantrium.
Revonto Dantrium Ryanodex
* Assumes a 140-lb patient at 2.5 mg/kg.
(Par Pharmaceutical).
Regardless of which antidote you stock, chances are you'll never
use it. The overwhelming odds are that you'll never experience an
episode of MH, an inherited and potentially fatal disorder triggered by
certain anesthesia agents in genetically susceptible individuals.
Experts say you should use expired product in MH-preparedness staff
drills.
— Jim Burger
S E P T E M B E R 2 0 1 4 | O U T P AT I E N T S U R G E R Y M A G A Z I N E O N L I N E
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