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DEX YCU, the DEX YCU logo, and the EyePoint logo are registered trademarks of EyePoint Pharmaceuticals, Inc. © 2020 EyePoint Pharmaceuticals, Inc. All rights reserved. 480 Pleasant Street, Suite B300, Watertown, MA 02472 07/2020 US-DEX-2000096 Ready to support you and your patients INDICATION AND USAGE DEXYCU ® (dexamethasone intraocular suspension) 9% is indicated for the treatment of postoperative inflammation. IMPORTANT SAFETY INFORMATION CONTRAINDICATIONS None. WARNINGS AND PRECAUTIONS Increase in Intraocular Pressure • Prolonged use of corticosteroids, including DEXYCU, may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision • Steroids should be used with caution in the presence of glaucoma Delayed Healing • The use of steroids after cataract surgery may delay healing and increase the incidence of bleb formation • In those diseases causing thinning of the cornea or sclera, perforations have been known to occur with the use of corticosteroids Exacerbation of Infection • The use of DEXYCU, as with other ophthalmic corticosteroids, is not recommended in the presence of most active viral diseases of the cornea and conjunctiva including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella, and also in mycobacterial infection of the eye and fungal disease of ocular structures WARNINGS AND PRECAUTIONS (cont'd) Exacerbation of Infection (cont'd) • Use of a corticosteroid in the treatment of patients with a history of herpes simplex requires caution and may prolong the course and may exacerbate the severity of many viral infections • Fungal infections of the cornea are particularly prone to coincidentally develop with long-term local steroid application and must be considered in any persistent corneal ulceration where a steroid has been used or is in use. Fungal culture should be taken when appropriate • Prolonged use of corticosteroids may suppress the host response and thus increase the hazard of secondary ocular infections. In acute purulent conditions, steroids may mask infection or enhance existing infection Cataract Progression • The use of corticosteroids in phakic individuals may promote the development of posterior subcapsular cataracts ADVERSE REACTIONS • The most commonly reported adverse reactions occurred in 5-15% of subjects and included increases in intraocular pressure, corneal edema and iritis Please see brief summary of full Prescribing Information on adjacent page. To learn more about how DEXYCU ® (dexamethasone intraocular suspension) 9% can help, visit DEXYCU.com or call 1-833-EYEPOINT (1-833-393-7646). The future may seem like it 's filled with questions, but EyePoint Pharmaceuticals wants to help provide answers. You and your patients need certainty, and there may be concerns about what your practice may experience. You may be considering ways to help: Ease patient concerns about exposure Minimize patients touching their faces Reduce office and pharmacy visits for patients and caregivers